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Food-drug interactions

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Here are some of the most dangerous food-drug interactions that pharmacists can help prevent:
1. Calcium-Rich Foods + Antibiotics. ...
2. Pickled, Cured, and Fermented Foods + MAIOs. ...
3. Vitamin K-Rich Foods + Warfarin. ...
4. Alcohol + Prescription Stimulants. ...
5. Grapefruit and Grapefruit Juice + Statins.

5 Dangerous Food-Drug Interactions - Pharmacy Times

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Eating with High Blood Pressure: Food and Drinks to Avoid
• Salt.
• Deli meat.
• Frozen pizza.
• Pickles.
• Canned soups.
• Tomato products.
• Sugar.
• Packaged foods.
More items...
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Eating with High Blood Pressure: 9 Foods and Drinks to Avoid
www.healthline.com › high-blood-pressure-hypertension

Search for: What foods interfere with high blood pressure medication?
https://www.healthline.com/health/high-blood-pressure-hypertension/foods-to-avoid
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Common Food-Drug Interactions
Jacqueline Boucher, PA-C
Caughman Health Center Pediatrics
Taking medicine is a normal routine for many people, but there are many aspects to think about to avoid unwanted interactions. Age, weight, sex, medical conditions, dose of medicine, other medications, vitamins and herbal supplements can affect any drug taken. Some drugs can work faster, slower, better or worse on an empty stomach while others will upset an empty stomach. Alcohol also has significant effects on medication use. Drinking alcohol while taking medication, or before and after, can affect how the drug works in the body.
When a food affects medications in the body, this is called food-drug interaction. Food can prevent medicine from working the way it should and can cause medicinal side effects to become better or worse and/or cause new side effects to occur. Drugs can also change the way the body uses food. There are a variety of food and drug interactions that can occur, but here is a small list of common drugs and how food affects the way they are used in the body.
• Green, leafy vegetables, which are high in vitamin K, can decrease how well aspirin thins the blood. Consuming the same amount of green-leafy vegetables each day will decrease this interaction.
• Grapefruit juice alters the way the body absorbs statins (cholesterol-lowering drugs) like Lipitor in the blood. It can cause these drugs to be absorbed in higher than normal amounts resulting in a greater risk of side effects.
• Calcium channel blockers are prescribed for high blood pressure and are also affected by grapefruit juice. Grapefruit juice changes the way this drug breaks down in the body and may cause overly high levels of the drug in the blood, raising the risk of side effects.
• Dairy products such as milk, yogurt and cheese decrease the absorption of antibiotics. Try to eat meals one to two hours before taking these to avoid this interaction.
• Alcohol affects insulin or oral diabetic pills. Alcohol prolongs the effects of these drugs, which leads to low blood sugar.
• Moderate pain reliever drugs with acetaminophen should not be taken with alcohol because it has a higher chance of causing severe liver damage. Antihistamines, like Benadryl, should not be taken with alcohol because it will cause increased drowsiness.
This is only a small list of drugs that are affected by food, but it is important to be informed about common medications that are consumed. Most medications and over-the-counter drugs have warnings stating when it is ok and when it is not ok to consume them, so do not be alarmed about taking any current
Diet can have a big impact on your blood pressure. Salty and sugary foods, and foods high in saturated fats, can increase blood pressure. Avoiding them can help you get and maintain a healthy blood pressure.
If you have high blood pressure, the American Heart Association recommend eating plenty of fruits, vegetables, lean protein, and whole grains.
At the same time, they recommend avoiding red meat, salt (sodium), and foods and drinks that contain added sugars. These foods can keep your blood pressure elevated.
High blood pressure, or hypertension, affects about 45%Trusted Source of Americans. Hypertension can cause health problems over time, including heart disease and stroke.
This article looks at what foods to avoid or limit if you have high blood pressure, along with ideas for a heart-healthy eating pattern.
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1. Salt or sodium
Salt, or specifically the sodium in salt, is a major contributorTrusted Source to high blood pressure and heart disease. This is because of how it affects fluid balance in the blood.
Table salt is around 40% sodium. The AHA recommend getting no more than 2,300 milligrams (mg) of sodium — the equivalent of 1 teaspoon of salt — each day.
Most of the sodium in the American diet comes from packaged, processed food rather than what you add at the table. Sodium may be hidden in unexpected places.
The following foods, known as the “salty six,” are major contributors to people’s daily salt intake:
• breads and rolls
• pizza
• sandwiches
• cold cuts and cured meats
• soup
• burritos and tacos
Read more about the benefits and risks of eating salt here.
2. Deli meat
Processed deli and lunch meats are often packed with sodium. That’s because manufacturers cure, season, and preserve these meats with salt.
According to the United States Department of Agriculture (USDA) database, just two slices of bologna contain 910 mgTrusted Source of sodium. One frankfurter, or hot dog, contains 567 mgTrusted Source.
Adding other high-salt foods, such as bread, cheese, various condiments, and pickles, mean that a sandwich can become loaded with sodium very easily.
Read more about how processed meat affects health here.
3. Frozen pizza
The combination of ingredients in frozen pizzas means they’re high in sugar, saturated fat, and sodium. Frozen pizza can have especially high levels of sodium.
Cheese is often high in sodium, with just two slices of American cheese containing 512 mgTrusted Source of sodium. This is generally in combination with a salty or sugary pizza dough and crust, cured meats, and tomato sauce.
To maintain flavor in the pizza once it’s been cooked, manufacturers often add a lot of salt.
One 12 inch pepperoni pizza, cooked from frozen, contains 3,140 mgTrusted Source of sodium, which is well above the daily limit of 2,300 mg.
As a substitute, try making a healthful pizza at home, using homemade dough, low-sodium cheese, and your favorite vegetables as toppings.
Get some tips for making a healthful pizza here.
4. Pickles
Preserving any food requires salt. It stops the food from decaying and keeps it edible for longer.
The longer vegetables sit in canning and preserving liquids, the more sodium they pick up.
One small pickled cucumber contains 447 mgTrusted Source of sodium.
That said, reduced-sodium options are available.
5. Canned soups
Canned coups are simple and easy to prepare, especially when you’re crunched for time or not feeling well.
However, canned soups are high in sodium. Canned and packaged broths and stocks may contain similar amounts. This means they can elevate your blood pressure.
One can of tomato soup contains 1,110 mgTrusted Source of sodium, while a can of chicken and vegetable soup contains 2,140 mgTrusted Source.
Try choosing low- or reduced-sodium soups instead, or make your own soup at home from fresh ingredients.
6. Canned tomato products
Most canned tomato sauces, pasta sauces, and tomato juices are high in sodium. This means that they can cause raise your blood pressure, especially if you already have high blood pressure.
One serving (135 g) of marinara sauce contains 566 mgTrusted Source of sodium. One cup of tomato juice contains 615 mgTrusted Source.
You can find low- or reduced-sodium versions for most tomato products.
To lower your blood pressure, choose these alternatives or use fresh tomatoes, which are rich in an antioxidant called lycopene. Fresh vegetables have many benefits for heart health.
7. Sugar
Sugar can increase your blood pressure in several ways.
Research shows that sugar — and especially sugar-sweetened drinks — contributes to weight gain in adults and children. Overweight and obesity predisposeTrusted Source people to high blood pressure.
Added sugar may also have a direct effect on increasing blood pressure, according to a 2014 review.
One study in females with high blood pressure reported that decreasing sugar by 2.3 teaspoons could result in an 8.4 mmHg drop in systolic and a 3.7 mmHg drop in diastolic blood pressure.
The AHA recommends the following daily added sugar limits:
• 6 teaspoons, or 25 grams, for females
• 9 teaspoons, or 36 grams, for males
8. Processed foods with trans or saturated fat
To keep the heart healthy, people should reduce saturated fats and avoid trans fats. This is especially true for people with high blood pressure.
Trans fats are artificial fats that increase packaged foods’ shelf life and stability.
However, they also raiseTrusted Source your bad (LDL) cholesterol levels and lower your good (HDL) cholesterol levels, which can increase the risk of hypertension.
Saturated fats also increaseTrusted Source the levels of LDL cholesterol in the blood.
Trans fats are especially poor for your health and are linked withTrusted Source poor heart health, including an increased risk of:
• heart disease
• stroke
• type 2 diabetes
Packaged, pre-prepared foods often contain trans fats and saturated fats, alongside high amounts of sugar, sodium, and low-fiber carbohydrates.
Saturated fats are mostly found in animal products, including:
• full-fat milk and cream
• butter
• red meat
• chicken skin
The AHA recommends reducing intake of both saturated and trans fats to help keep the heart healthy.
One way to reduce your saturated fat intake is to replace some animal foods with healthful plant-based alternatives.
Many plant-based foods contain healthful monounsaturated and polyunsaturated fatty acids. Examples of plant-based foods include:
• nuts
• seeds
• olive oil
• avocado
According to some researchTrusted Source, full-fat dairy doesn’t raise blood pressure.
9. Alcohol
Drinking too much alcohol can increaseTrusted Source your blood pressure.
If you have high blood pressure, your doctor might recommend that you reduce the amount of alcohol you drink.
In people who do not have hypertension, limiting alcohol intake can help reduce their risk of developing high blood pressure.
Alcohol can also preventTrusted Source any blood pressure medications that you may be taking from working effectively through drug interactions.
In addition, many alcoholic drinks are high in sugar and calories. Drinking alcohol can contributeTrusted Source to overweight and obesity, which can increase the risk of hypertension.
If you drink, the AHA recommends limiting your alcohol intake to two drinks per day for males and one drink per day for females.
If cutting back on alcohol is difficult, talk to your doctor for advice.
What are the best diets for high blood pressure?
Following a heart-heathy diet can actively reduce your blood pressure, both in the short term and long term.
Foods that contain potassium can quicklyTrusted Source reduce blood pressure, because potassium offsets the effects of sodium.
Foods that contain nitrates can reduceTrusted Source blood pressure, too, including beets and pomegranate juice. These foods also contain other health-healthy components, including antioxidants and fiber.
Read about the best foods for high blood pressure here.
The AHA recommends following the DASH diet to help manage blood pressure. DASH stands for dietary approaches to stop hypertension.
This diet involves eating plenty of fruits, vegetables, whole grains, low-fat dairy, and lean protein to help reduce blood pressure and maintain healthy levels.
When choosing canned or processed foods, opt for reduced-sodium, no-sodium, or trans fat-free options.
The bottom line
Diet can have a big impact on your blood pressure.
Foods high in salt, sugar, and saturated or trans fats can increase blood pressure and damage your heart health. By avoiding these foods, you can keep your blood pressure in check.
A diet full of fruits, vegetables, whole grains, and lean protein can help keep your heart healthy.
Last medically reviewed on August 12, 2020
Medically reviewed by Amy Richter, RD — Written by Kimberly Holland — Updated on August 12, 2020
13 Foods That Are Good for High Blood Pressure
We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Here’s our process.
What is hypertension?
Hypertension, or high blood pressure, refers to the pressure of blood against your artery walls. Over time, high blood pressure can cause blood vessel damage that leads to heart disease, kidney disease, stroke, and other problems. Hypertension is sometimes called the silent killer because it produces no symptoms and can go unnoticed — and untreated — for years.
According to the Centers for Disease Control and PreventionTrusted Source (CDC), an estimated 75 million Americans have high blood pressure. Many risk factors for high blood pressure are out of your control, such as age, family history, gender, and race. But there are also factors you can control, such as exercise and diet. A diet that can help control blood pressure is rich in potassium, magnesium, and fiber and lower in sodium.
Read on to learn which foods can help you fight hypertension.


13 foods that help lower blood pressure
1. Leafy greens
Potassium helps your kidneys get rid of more sodium through your urine. This in turn lowers your blood pressure.
Leafy greens, which are high in potassium, include:
• romaine lettuce
• arugula
• kale
• turnip greens
• collard greens
• spinach
• beet greens
• Swiss chard
Canned vegetables often have added sodium. But frozen vegetables contain as many nutrients as fresh vegetables, and they’re easier to store. You can also blend these veggies with bananas and nut milk for a healthy, sweet green juice.
2. Berries
Berries, especially blueberries, are rich in natural compounds called flavonoids. One study found that consuming these compounds might prevent hypertension and help lower blood pressure.
Blueberries, raspberries, and strawberries are easy to add to your diet. You can put them on your cereal or granola in the morning, or keep frozen berries on hand for a quick and healthy dessert.
3. Red beets
Beets are high in nitric oxide, which can help open your blood vessels and lower blood pressure. Researchers also found that the nitrates in beetroot juice lowered research participants’ blood pressure within just 24 hours.
You can juice your own beets or simply cook and eat the whole root. Beetroot is delicious when roasted or added to stir-fries and stews. You can also bake them into chips. Be careful when handling beets — the juice can stain your hands and clothes.
4. Skim milk and yogurt
Skim milk is an excellent source of calcium and is low in fat. These are both important elements of a diet for lowering blood pressure. You can also opt for yogurt if you don’t like milk.
According to the American Heart Association, women who ate five or more servings of yogurt a week experienced a 20 percent reduction in their risk for developing high blood pressure.
Try incorporating granola, almond slivers, and fruits into your yogurt for extra heart-healthy benefits. When buying yogurt, be sure to check for added sugar. The lower the sugar quantity per serving, the better.
5. Oatmeal
Oatmeal fits the bill for a high-fiber, low-fat, and low-sodium way to lower your blood pressure. Eating oatmeal for breakfast is a great way to fuel up for the day.
Overnight oats are a popular breakfast option. To make them, soak 1/2 cup of rolled oats and 1/2 cup of nut milk in a jar. In the morning, stir and add berries, granola, and cinnamon to taste.
6. Bananas
Eating foods that are rich in potassium is better than taking supplements. Slice a banana into your cereal or oatmeal for a potassium-rich addition. You can also take one to go along with a boiled egg for a quick breakfast or snack.
7. Salmon, mackerel, and fish with omega-3s
Fish are a great source of lean protein. Fatty fish like mackerel and salmon are high in omega-3 fatty acids, which can lower blood pressure, reduce inflammation, and lower triglycerides. In addition to these fish sources, trout contains vitamin D. Foods rarely contain vitamin D, and this hormone-like vitamin has properties that can lower blood pressure.
One benefit of preparing fish is that it’s easy to flavor and cook. To try it, place a fillet of salmon in parchment paper and season with herbs, lemon, and olive oil. Bake the fish in a preheated oven at 450°F for 12-15 minutes.
8. Seeds
Unsalted seeds are high in potassium, magnesium, and other minerals known to reduce blood pressure. Enjoy ¼ cup of sunflower, pumpkin, or squash seeds as a snack between meals.
9. Garlic and herbs
One reviewTrusted Source notes that garlic can help reduce hypertension by increasing the amount of nitric oxide in the body. Nitric oxide helps promote vasodilation, or the widening of arteries, to reduce blood pressure.
Incorporating flavorful herbs and spices into your daily diet can also help you cut back on your salt intake. Examples of herbs and spices you can add include basil, cinnamon, thyme, rosemary, and more.
10. Dark chocolate
A 2015 study found that eating dark chocolate is associated with a lower risk for cardiovascular disease (CVD). The study suggests that up to 100 grams per day of dark chocolate may be associated with a lower risk of CVD.
Dark chocolate contains more than 60 percent cocoa solids and has less sugar than regular chocolate. You can add dark chocolate to yogurt or eat it with fruits, such as strawberries, blueberries, or raspberries, as a healthy dessert.
Find a great selection of dark chocolate on Amazon.com.
11. Pistachios
Pistachios are a healthy way to decrease blood pressure by reducing peripheral vascular resistance, or blood vessel tightening, and heart rate. One studyTrusted Source found that a diet with one serving of pistachios a day helps reduce blood pressure.
You can incorporate pistachios into your diet by adding them to crusts, pesto sauces, and salads, or by eating them plain as a snack.
12. Olive oil
Olive oil is an example of a healthy fat. It contains polyphenols, which are inflammation-fighting compounds that can help reduce blood pressure.
Olive oil can help you meet your two to three daily servings of fat as part of the DASH diet (see below for more about this diet). It’s also a great alternative to canola oil, butter, or commercial salad dressing.
13. Pomegranates
Pomegranates are a healthy fruit that you can enjoy raw or as a juice. One study concluded that drinking a cup of pomegranate juice once a day for four weeks helps lower blood pressure over the short term.
Pomegranate juice is tasty with a healthy breakfast. Be sure to check the sugar content in store-bought juices, as the added sugars can negate the health benefits.
The DASH diet and recommended foods
Dietary recommendations for lowering blood pressure, such as the Dietary Approaches to Stop HypertensionTrusted Source (DASH) diet, include reducing your intake of fat, sodium, and alcohol. Following the DASH diet for two weeks can lower your systolic blood pressure (the top number of a blood pressure reading) by 8-14 points.
Serving suggestions for the DASH diet include:
Foods Serving per day
sodium no more than 2,300 mg on a traditional diet or 1,500 mg on a low-sodium diet
dairy (low-fat) 2 to 3
healthy fats (avocado, coconut oil, ghee) 2 to 3
vegetables 4 to 5
fruit 4 to 5
nuts, seeds, and legumes 4 to 5
lean meat, poultry, and fish 6
whole grains 6 to 8
In general, you should eat more low-fat protein sources, whole grains, and plenty of fruits and vegetables. The DASH guidelines also suggest eating more foods rich in potassium, calcium, and magnesium.
In general, you should eat more low-fat protein sources, whole grains, and plenty of fruits and vegetables. The DASH guidelines also suggest eating more foods rich in potassium, calcium, and magnesium. The guidelines also recommend no more than:
• Five servings of sweets per week
• One drink per day for women
• Two drinks per day for men
One study found that a high-fat (full fat) DASH diet reduces the same amount of blood pressure as the traditional DASH diet. Another review looked at results of 17 studies and found that the DASH diet reduced blood pressure on average by 6.74 mmHg for systolic blood pressure and 3.54 mmHg points for diastolic blood pressure.
The bottom line
Through a heart-healthy diet, you can reduce your risks for hypertension and promote good health overall.

Medically reviewed by Natalie Butler, R.D., L.D. — Written by Mary Ellen Ellis — Updated on June 29, 2020

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