**Ramipril- 라미프릴* 고혈압/심장마비/뇌졸중예방 *(ACE) 앤지오텐신 전환효소 억제제 inhibitors.-angiotensin converting enzyme > 건강/ 약품 Drug / 보조 약품

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* 라미프릴,고혈압 및 심근경색후 심부전등의 적응증- *Ramipril *coversyl-angiotensin converting enzyme (ACE) inhibitors.
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https://en.wikipedia.org/wiki/Ramipril
https://ko.wikipedia.org/wiki/ACE_%EC%96%B5%EC%A0%9C%EC%A0%9C

트리테이스정2.5밀리그람(라미프릴) - 의약품안전나라

라미프릴 from nedrug.mfds.go.kr
1. 고혈압. ① 이뇨제를 투여받고 있지 않은 환자 성인 : 라미프릴로서 초회량으로 1일 1회 2.5㎎을 식사중 또는 식사후 다량의 물과 함께 경구투여한다. · 2. 심근경색 후 ...
라미프릴, 심장병 감소에 효과

라미프릴은 심장마비나 뇌졸중 발병을 예방함은 물론 이로 인해 수술이나 병원에 입원할 필요성을 감소시키는 결과를 가져오고 있는 약물이다. 최근 수년간 라미프릴을
'라미프릴제제, 혈관부종 부작용 주의'

변경된 허가사항에 따르면 승모판협착증 및 고칼륨혈증 환자에게 라미프릴 제제를 처방해서는 안된다. 동맥 저혈압은 관상동맥경화 또는 뇌혈관 부전이 있는 경우 위험할 ...

라미프릴은 국내에서 1992년부터 임상적으로 고혈압 치료제인 ACE(안지오텐신 전환효소) 저해제로 쓰여져 온 약물로 라미프릴의 심장/혈관 보호작용에 관한 적응증은, 영국 ...

혈관

심근경색ace 억제제

May 21, 2021 — 엔트레스토가 라미프릴 대비 급성심근경색(AMI) 치료 후 심혈관 사망 및 심부전 입원 등 개선에 이점이 없었던 것이다.

라미프릴, 급성신부전 등 부작용보고 ...

Apr 8, 2010 — 고혈압약 라미프릴제제에 결막염, 치명적 췌장염, 급성신부전 등의 부작용이 보고되 사용상 주의사항이 변경된다. 7일 식약청은 라미프릴 ...

라미프릴, 심혈관질환에 효과 우수

HOPE study는 고혈압 및 심근경색후 심부전등의 적응증에 처방되고 있는 ACE 저해제인 '라미프릴'(Ramipril, 제품명 : 트리테이스 )에 대한 대규모 임상시험이다.

라미프릴 10mg
성인 : 라미프릴로서 초회량으로 1일 1회 2.5mg을 식사중 또는 식사후 다량의 물과 함께 경구투여한다. 단, 환자의 반응에 따라 2-3주 간격으로 처음에는 1일 5mg까지,
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ACE 억제제
앤지오텐신 전환효소 억제제(ACE 억제제)는 고혈압, 울혈성 심부전의 1차 치료제로 쓰이는 약물 종류이다. 이 그룹에 속한 약물은 혈관을 이완시키고 혈액의 부피를
.이 그룹에 속한 약물은 혈관을 이완시키고 혈액의 부피를 낮춤으로서 혈압을 낮추고 심장의 산소소모량을 감소시킨다. 약물들은 레닌 앤지오텐신계의 중요한 요소인 앤지오텐신 전환효소를 억제한다.


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https://www.google.ca/search?q=%EB%9D%BC%EB%AF%B8%ED%94%84%EB%A6%B4&hl=en&sxsrf=APwXEdcBgRKLQ5nENZdbLSElwfoDUio5tw%3A1682078057872&ei=aXlCZKDsNMKE0PEPltSJiAE&oq=fkalv&gs_lcp=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&sclient=gws-wiz-serp
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Ramipril
Medication
Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication used to treat high blood pressure, heart failure, and diabetic kidney disease. Wikipedia
Molar mass: 416.511 g/mol
ChemSpider ID: 4514937
Formula: C23H32N2O5
Classification: ACE inhibitor
Metabolism: Liver, to ramiprilat
Routes of administration: By mouth
Protein binding: 73% (ramipril); 56% (ramiprilat
https://www.google.ca/search?q=ramipril&biw=1261&bih=625&sxsrf=APwXEdcajFWt3NZJmS4sCPXck1aZDRNx2g%3A1680967501808&ei=TYcxZOb4MO2y0PEP4dC5gAk&ved=0ahUKEwim08v2y5r-AhVtGTQIHWFoDpAQ4dUDCA8&uact=5&oq=ramipril&gs_lcp=Cgxnd3Mtd2l6LXNlcnAQAzIKCAAQigUQsQMQQzIHCAAQigUQQzIHCAAQigUQQzIHCAAQigUQQzIICAAQigUQkQIyBwgAEIoFEEMyBwgAEIoFEEMyBwgAEIoFEEMyDQgAEIoFELEDEIMBEEMyCggAEIAEELEDEAo6BwgjECcQnQI6BAgjECc6EQguEIMBEMcBELEDENEDEIAEOgUILhCABDoOCC4QgAQQsQMQgwEQ1AI6BQgAEIAEOgsIABCABBCxAxCDAToLCAAQigUQsQMQgwE6CwguEIAEELEDEIMBOgoILhCKBRCxAxBDOg0ILhCKBRCxAxCDARBDOggIABCABBCLAzoKCAAQgAQQChCLA0oECEEYAFAAWKgoYJgtaABwAXgAgAHuAYgB2AiSAQUyLjQuMpgBAKABAbgBAsABAQ&sclient=gws-wiz-serp
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앤지오텐신 전환효소 억제제(ACE 억제제)는 고혈압, 울혈성 심부전의 1차 치료제로 쓰이는 약물 종류이다.

이 그룹에 속한 약물은 혈관을 이완시키고 혈액의 부피를 낮춤으로서 혈압을 낮추고 심장의 산소소모량을 감소시킨다. 약물들은 레닌 앤지오텐신계의 중요한 요소인 앤지오텐신 전환효소를 억제한다.

자주 처방되는 ACE억제제로는 Perindopril, 캡토프릴, Enalapril, Lisinopril 및 Ramipril이 있다.
DIN (Drug Identification Number)
02123274 COVERSYL 2MG TABLET
02123282 COVERSYL 4MG TABLET
02246624 COVERSYL 8MG TABLET
About this Medication
How does this medication work? What will it do for me?
What form(s) does this medication come in?
How should I use this medication?
Who should NOT take this medication?
What side effects are possible with this medication?
Are there any other precautions or warnings for this medication?
What other drugs could interact with this medication?
DRUGS
CONDITIONS
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
How does this medication work? What will it do for me?
Perindopril belongs to the class of medications called angiotensin converting enzyme (ACE) inhibitors. It is used to treat high blood pressure. It helps to control blood pressure by relaxing blood vessels. Perindopril may be used alone or in combination with other medications that reduce blood pressure, especially thiazide diuretics (water pills).

Perindopril is also used to treat mild-to-moderate congestive heart failure in combination with other medications such as diuretics and digoxin. It may also be used to decrease the risk of further cardiac (heart) events after a recent heart attack or for people with coronary artery disease.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

What form(s) does this medication come in?
2 mg
Each white, round, film-coated, biconvex tablet contains 2 mg of perindopril erbumine. Nonmedicinal ingredients: hydrophobic colloidal silica, lactose monohydrate, magnesium stearate, and microcrystalline cellulose.

4 mg
Each light green, rod-shaped, film-coated tablet, engraved with a symbol on one face and scored on both edges contains 4 mg of perindopril erbumine. Nonmedicinal ingredients: chlorophyllin (E141ii) aluminium lake, hydrophobic colloidal silica, lactose monohydrate, magnesium stearate, and microcrystalline cellulose.

8 mg
Each green, round, film-coated, biconvex tablet, engraved with a symbol on one face and another symbol on the other contains 8 mg of perindopril erbumine. Nonmedicinal ingredients: chlorophyllin (E141ii) aluminium lake, hydrophobic colloidal silica, lactose monohydrate, magnesium stearate, and microcrystalline cellulose.

How should I use this medication?
To treat high blood pressure or after a heart attack, the usual starting dose of perindopril is 4 mg taken once daily. The dose may be increased after 2 weeks up to a maximum of 8 mg once daily depending on blood pressure control. Perindopril may be used alone or in combination with other medications to reduce blood pressure.

When used to treat congestive heart failure, the starting dose of perindopril is 2 mg. It may then be increased to 4 mg once daily depending on the effect of the medication and side effects.

For best results, the tablets should be taken before a meal and on an empty stomach. Once-daily doses should be taken in the morning before breakfast. Seniors and people with kidney disease may require smaller doses.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones given here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by the doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Who should NOT take this medication?
Do not take perindopril if you:

are allergic to perindopril or any ingredients of the medication
are pregnant or may become pregnant
are breast-feeding
are taking the medication sacubitril-valsartan
have been diagnosed with hereditary angioedema
have had angioedema (a serious allergic reaction which causes the area around the throat and tongue to swell) after taking any other ACE inhibitors (e.g., captopril, enalapril, ramipril)
have any condition that makes you lactose intolerant
have diabetes or kidney disease and are taking aliskiren
are receiving dialysis or any other type of blood filtration
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

cold symptoms (e.g., nasal congestion, runny nose, cough, sore throat)
cough (dry, persistent)
diarrhea
difficulty maintaining an erection
dizziness
drowsiness
feeling weak
headache
loss of taste
metallic taste in mouth
swelling of the hands, feet, or ankles
trouble sleeping
unusual tiredness
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

chest pain
cold hands or feet
pounding or irregular heartbeat
ringing in the ears
severe abdominal pain with or without nausea and vomiting
signs of bleeding (e.g., unusual nosebleeds, blood in urine, coughing blood, bruising easily, cuts that won't stop bleeding)
signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
signs of fluid and electrolyte imbalance (e.g., drowsiness, muscle pain or cramps, weakness, irregular heartbeat)
signs of infection (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)
signs of kidney problems (e.g., increased urination at night, decreased urine production, blood in the urine, change of urine colour)
signs of low blood pressure (e.g., dizziness, lightheadedness, fainting)
signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
signs of too much potassium in the body (e.g., confusion, irregular heartbeat; nervousness; numbness or tingling in hands, feet, or lips; shortness of breath or difficulty breathing; weakness or heaviness of legs)
skin rash, with or without itching, fever, or joint pain
swelling of the hands, feet or ankles
worsening symptoms of psoriasis
Stop taking the medication and seek immediate medical attention if any of the following occur:

signs of a serious allergic reaction (i.e., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
signs of heart attack (e.g., sudden chest pain or pain radiating to back, down arm, jaw; sensation of fullness of the chest; nausea; vomiting; sweating; anxiety)
signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, swollen abdomen)
signs of a severe skin reaction such as blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort
signs of stroke (e.g., sudden or severe headache; sudden loss of coordination; vision changes; sudden slurring of speech; or unexplained weakness, numbness, or pain in arm or leg)
signs of angioedema (e.g., swollen mouth, lips, tongue, difficulty swallowing or breathing)